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Title: | Desain Fermentasi Gandarusa oleh Aspergillus tamarii dengan Respon Kapasitas Antioksidan, Total Fenolik dan Flavonoid. |
Other Titles: | Design of Gendarussa Fermentation by Aspergillus tamarii with Response on Antioxidant Capacity, Total Flavonoids and Phenolics |
Authors: | Syaefudin, Syaefudin Nurcholis, Waras Putra, Syahrul Alam |
Issue Date: | 2023 |
Publisher: | IPB University |
Abstract: | Tanaman obat di Indonesia sangat berlimpah sehingga berpotensi dijadikan
bahan baku obat, salah satunya gandarusa (Justicia gendarussa Burm F.).
Gandarusa merupakan tanaman obat yang termasuk ke dalam kelompok tanaman
perdu yang memiliki potensi sebagai antioksidan. Potensi tersebut disebabkan
adanya senyawa metabolit sekunder seperti fenolik dan flavonoid. Aspergillus
tamarii adalah fungi yang berfilamen sehingga dipercaya mampu meningkatkan
senyawa metabolit sekunder melalui proses fermentasi media padat. Tujuan
penelitian ini untuk mendapatkan desain formula fermentasi pada gandarusa oleh
A.tamarii dengan respon kapasitas antioksidan, kadar total fenolik (TPC) dan
flavonoid (TFC). Desain fermentasi dilakukan dengan menggunakan software
Design Expert metode two half level factorial. Hasil penelitian menunjukkan faktor
fermentasi yang berpengaruh terhadap TPC, TFC, kapasitas antioksidan 2,2-
diphenyl-1-picrylhydrazyl (DPPH) dan ferric reducing antioxidant power (FRAP)
adalah waktu, suhu, dan konsentrasi inokulum. Solusi desain fermentasi gandarusa
yang didapat waktu fermentasi 14 hari, suhu fermentasi 45 ˚C, kelembaban 2 mL,
dan konsentrasi inokulum 100%. The medicinal plants in Indonesia are abundant and have the potential to be used as raw materials for medicine production, one of which is gendarusa (Justicia gendarussa Burm F.). Gendarusa is a medicinal plant that belongs to the group of perennial plants and has the potential to be an antioxidant. This potential is due to the presence of secondary metabolites such as phenolics and flavonoids. Aspergillus tamarii is a filamentous fungus believed to be capable of increasing secondary metabolite compounds through solid-state fermentation. This research aimed to obtain a fermentation formula design for gendarusa by A.tamarii with response variables of antioxidant capacity, total phenolic content (TPC), and total flavonoid content (TFC). The fermentation design was conducted using the Design Expert software with a two-half-level factorial method. The research results showed that the fermentation factors affecting TPC, TFC, 2,2-diphenyl-1-picrylhydrazyl (DPPH) antioxidant capacity, and ferric-reducing antioxidant power (FRAP) are time, temperature, and inoculum concentration. The fermentation design solution for gendarusa obtained a fermentation time of 14 days, a fermentation temperature of 45 ˚C, a moisture content of 2 mL, and an inoculum concentration of 100%. |
URI: | http://repository.ipb.ac.id/handle/123456789/126206 |
Appears in Collections: | UT - Biochemistry |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01 Watermark (Cover) - SKRIPSI - (G84190040) SYAHRUL ALAM PUTRA.pdf Restricted Access | Cover | 477.3 kB | Adobe PDF | View/Open |
02 Watermark (Fullteks) - SKRIPSI - (G84190040) SYAHRUL ALAM PUTRA.pdf Restricted Access | Fulltext | 1.14 MB | Adobe PDF | View/Open |
03 Watermark (Lampiran) - SKRIPSI - (G84190040) SYAHRUL ALAM PUTRA.pdf Restricted Access | Lampiran | 595.14 kB | Adobe PDF | View/Open |
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