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http://repository.ipb.ac.id/handle/123456789/115453
Title: | Pengaruh Intervensi Nasi Rumput Laut terhadap Kondisi Stres Oksidatif pada Penderita Prediabetes dan Diabetes |
Other Titles: | The Effect of Seaweed Rice Intervention on Oxidative Stress Conditions in Prediabetes and Diabetic Patients |
Authors: | Damayanthi, Evy Purwaningsih, Sri Mustika, Gina |
Issue Date: | 6-Dec-2022 |
Publisher: | IPB University |
Abstract: | Hiperglikemia pada penderita prediabetes dan diabetes melitus tipe 2 akan
meningkatkan terbentuknya radikal bebas. Peningkatan radikal bebas dalam tubuh
yang tidak disertai asupan antioksidan yang cukup akan menimbulkan stres
oksidatif. Nasi dengan tambahan rumput laut signifikan menurunkan kadar glukosa
darah pada tikus diabetes namun masih sangat terbatas informasi mengenai
pengaruh intervensi nasi rumput laut pada manusia. Penelitian ini bertujuan
menganalisis kebiasaan makan dan pengaruh intervensi nasi rumput laut terhadap
kadar glukosa darah serta aktivitas antioksidan pada penderita prediabetes dan DM
tipe 2. Penelitian ini berbasis desain quasi experimental dengan rancangan pre-post
with control yang dilakukan pada bulan Desember 2021−Agustus 2022. Jenis
pangan meliputi makanan pokok, protein hewani, protein nabati, sayur, buah,
makanan manis, dan fast food yang paling sering dikonsumsi subjek yaitu nasi, telur
ayam, tempe, wortel, pisang, kopi, mie instan. Berdasarkan uji Mann Whitney,
kadar GDP antara kelompok intervensi dan kontrol sebelum dan sesudah intervensi
menunjukkan adanya penurunan kadar glukosa darah meskipun tidak berbeda
signifikan (p>0.05). Hasil uji Mann Whitney untuk aktivitas SOD kedua kelompok
sebelum dan sesudah intervensi menunjukkan tidak ada perbedaan yang signifikan
(p>0.05). Berdasarkan penelitian yang dilakukan, nasi rumput laut memiliki potensi
untuk menurunkan kadar glukosa darah dan dapat meningkatkan aktivitas
antioksidan meskipun belum efektif. Hyperglycemia in prediabetes and diabetes mellitus (T2DM) people will increase the formation of free radicals. The increasing of free radicals without antioxidant enhancement will produce oxidative stress. Seaweed rice significantly lowered the blood glucose levels of diabetic rats but still very limited information about the effect of seaweed rice intervention on humans. This study aims to analyze eating habits and the effect of seaweed rice intervention on blood glucose levels and antioxidant activity in prediabetes and diabetes mellitus patients. This research is based on pre-post with control conducted on December 2021−August 2022. The types of food include staple foods, animal proteins, vegetable proteins, vegetables, fruits, sweet foods, and fast foods that are most commonly consumed by subjects are rice, eggs, tempeh, carrots, bananas, coffee, instant noodles. Based on Mann Whitney test on GDP levels between the intervention and control groups before and after the intervention showed a decrease in blood glucose levels although not significantly different (p>0.05). Mann Whitney test results for SOD activity of both groups before and after the intervention showed no significant difference (p>0.05). Based on this research, seaweed rice has benefits for lowering blood glucose levels and increasing the antioxidant activity although it’s not effective yet. |
URI: | http://repository.ipb.ac.id/handle/123456789/115453 |
Appears in Collections: | UT - Nutrition Science |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
COVER.pdf Restricted Access | Cover | 1.36 MB | Adobe PDF | View/Open |
I14180039_Gina Mustika.pdf Restricted Access | Full Text | 1.69 MB | Adobe PDF | View/Open |
LAMPIRAN.pdf Restricted Access | Lampiran | 1.81 MB | Adobe PDF | View/Open |
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