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Title: | Analisis Model Virus Chikungunya dengan Dua Cara Transmisi dan Imunitas Humoral |
Authors: | Sianturi, Paian Kusnanto, Ali Annisa, Mutia |
Issue Date: | 2022 |
Publisher: | IPB University |
Abstract: | Chikungunya merupakan penyakit yang menginfeksi sendi dan otot yang disebarkan oleh nyamuk Aedes Aegepty dan Aedes Albopictus. Virus chikungunya dapat menginfeksi sel rentan melalui dua cara, yaitu sel rentan langsung terinfeksi oleh virus atau sel terinfeksi lainnya. Tujuan penelitian ini yaitu menganalisis kestabilan titik tetap dan sensitivitas parameter dalam model, dan melakukan simulasi numerik. Dalam analisis ini dihasilkan dua titik tetap, yaitu titik tetap bebas penyakit dan titik tetap endemik. Hasil analisis sensitivitas dan simulasi numerik menyatakan bahwa untuk mencapai kondisi bebas penyakit diperlukan tindakan menurunkan laju transmisi sel rentan oleh sel virus dan sel terinfeksi lainnya, dan meningkatkan laju produksi antibodi. Chikungunya is a disease that infects joints and muscles spread by Aedes aegypti and Aedes albopictus mosquitoes. Chikungunya virus can infect susceptible cells in two ways: susceptible cells directly infected by virus or by other infected cells. The purpose of this study is to analyze the stability of the fixed point and the sensitivity of the parameters, and perform numerical simulations. In this analysis, two fixed points were produced, the disease-free and the endemic fixed points. The results of sensitivity analysis and numerical simulations indicate that to achieve stability of the disease-free point, it is necessary to reduce the rate of transmission of susceptible cells both by virus and by infected cells, also to increase the rate of antibody production. |
URI: | http://repository.ipb.ac.id/handle/123456789/114105 |
Appears in Collections: | UT - Mathematics |
Files in This Item:
File | Description | Size | Format | |
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Cover_TA_Mutia Annisa_G54170040.pdf Restricted Access | Cover | 669.87 kB | Adobe PDF | View/Open |
G54170040_Mutia Annisa.pdf Restricted Access | Fullteks | 690.68 kB | Adobe PDF | View/Open |
Lampiran_TA_Mutia Annisa_G54170040.pdf Restricted Access | Lampiran | 626.41 kB | Adobe PDF | View/Open |
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