Please use this identifier to cite or link to this item: http://repository.ipb.ac.id/handle/123456789/112494
Title: Uji Infusa Daun Pepaya (Carica papaya L.) sebagai Stimulator Stamina pada Mencit (Mus musculus)
Other Titles: Evaluation of Papaya (Carica papaya L.) Leaves Infusion as a Stamina Stimulator in Mice (Mus musculus)
Authors: Andriyanto
Manalu, Wasmen
Mahfudah, Ira
Issue Date: 14-Jul-2022
Publisher: IPB University
Abstract: Manusia dalam menjalankan aktivitas sehari-hari memerlukan energi untuk menjaga stamina atau daya tahan tubuh. Penurunan daya tahan tubuh akan menyebabkan individu cepat merasa lelah sehingga menghambat aktivitas sehari– hari. Pemilihan daun pepaya sebagai obat herbal stimulator stamina tubuh merupakan alternatif pengobatan tradisional untuk meningkatkan daya tahan tubuh. Penelitian ini bertujuan mempelajari efektivitas infusa daun pepaya sebagai stimulator stamina tubuh dalam berbagai dosis pada mencit, dan mengamati perubahan fisiologis tubuh meliputi suhu, frekuensi napas dan denyut jantung. Uji efektivitas stamina menggunakan metode ketahanan renang (swimming endurance). Penelitian ini menggunakan 25 ekor mencit jantan yang dikelompokkan menjadi lima kelompok: kontrol positif diberikan kafein, kontrol negatif diberikan akuades, dan kelompok perlakuan dengan diberikan infusa daun pepaya pada dosis 1, 3, dan 5 g/kg BB. Setiap kelompok terdiri atas lima ekor mencit. Data dianalisis menggunakan analysis of variance (ANOVA), kemudian dilanjutkan dengan uji Tukey. Hasil penelitian didapatkan dosis efektif pada uji stamina adalah 3 g/kg BB sebesar 80,18 detik. Daun papaya dapat menyebabkan perubahan fisiologis meliputi penurunan suhu, denyut jantung, dan frekuensi napas, namun masih dalam rentang normal. Kesimpulan penelitian ini adalah daun pepaya memiliki potensi sebagai stimulator stamina alami. Kata kunci: daun pepaya, infusa, stamina, stimulator.
Humans need energy to maintain stamina or endurance in order to carry out daily activities. Decrease in endurance will cause individuals to feel tired quickly, so it will inhibit daily activities. The selection of papaya leaves as an herbal medicine is an alternative to traditional medicine to increase endurance. This study aimed to investigate the effectiveness of papaya leaf infusion as a stamina stimulator with various doses in mice and to observe physiological changes in the body including temperature, respiratory rate, and heart rate. The stamina was tested using swimming endurance method. This study used 25 male mice which were divided into five groups: positive control (with caffeine), negative control (with distilled water), and the treatment groups with papaya leaf infusion at doses of 1, 3, and 5 g/kg BW. Each group consisted of five mice. The data collected were analyzed using Analysis of Variance (ANOVA), then continued with the Tukey test. The results showed that the effective dose in the stamina test was 3 g/kg BW for 80,18 seconds. Papaya leaf is able to cause physiological changes with a decrease in temperature, heart rate, and respiratory rate, but still in normal ranges. It is concluded that papaya leaf has the potential to be a natural stamina stimulator. Keywords: infusion, papaya leaf, stamina, stimulant.
URI: http://repository.ipb.ac.id/handle/123456789/112494
Appears in Collections:UT - Anatomy, Phisiology and Pharmacology

Files in This Item:
File Description SizeFormat 
COVER.pdf
  Restricted Access
Cover507.61 kBAdobe PDFView/Open
FULL TEXT.pdf
  Restricted Access
Full text833.57 kBAdobe PDFView/Open
LAMPIRAN.pdf
  Restricted Access
Lampiran343.45 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.