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http://repository.ipb.ac.id/handle/123456789/108266| Title: | Profil Ureum Nitrogen dan Kreatinin Darah pada Anjing yang Diberi Anti Caplak Berbahan Aktif Sarolaner di Direktorat Polisi Satwa Baharkam Polri Kelapa Dua Depok |
| Other Titles: | The Profile of Urea Nitrogen and Blood Creatinine in Dogs Treated by Sarolaner Anti tick Medication at Direktorat Polisi Satwa Baharkam Polri Kelapa Dua Depok |
| Authors: | Soviana, Susi Dewi, Tri Isyani Tungga Hidayah, Yola Salsabila |
| Issue Date: | 2021 |
| Publisher: | IPB University |
| Abstract: | Blood Urea Nitrogen (BUN) dan kreatinin darah merupakan parameter yang
dapat menunjukkan adanya gangguan fungsi ginjal. Penelitian ini bertujuan
menganalisis profil BUN dan kreatinin darah anjing yang diberikan anti caplak
berbahan aktif sarolaner. Sarolaner dalam dosis tunggal diberikan secara per oral
kepada 5 ekor anjing yang terinfestasi caplak, kemudian dilakukan pengambilan
darah melalui vena cephalica antebrachii. Pengukuran kadar BUN dan kreatinin
darah anjing dilakukan pada sehari sebelum perlakuan (H-0), seminggu (H+7),
dan sebulan setelah perlakuan (H+30). Alat yang digunakan untuk mengukur
kadar BUN dan kreatinin darah adalah Arkray Spotchem TM EZ 4430. Data profil
BUN dan kreatinin darah kelima anjing berdasarkan waktu pengamatan dianalisis
menggunakan uji one way ANOVA. Hasil penelitian menunjukkan bahwa tidak
terdapat perbedaan nyata pada kadar BUN dan kreatinin darah anjing di berbagai
waktu pengamatan (P>0.05). Rata-rata kadar BUN dan kreatinin darah anjing
masih berada dalam rentang normal. Hal ini dapat mengindikasikan bahwa
pemberian anti caplak berbahan aktif sarolaner dosis tunggal tidak mempengaruhi
fungsi ginjal. Blood Urea Nitrogen (BUN) and blood creatinine are parameters that can indicate impaired kidney function. This study aims to analyze the profile of BUN and blood creatinine in dogs that are treated with a single dose of sarolaner-active ingredients. Sarolaner in a single dose was given orally to 5 dogs that were infested with ticks, then blood was drawn through the cephalic antebrachii vein. Measurements of BUN and dog blood creatinine were carried out one day before treatment (H-0), a week (H+7), and a month after treatment (H+30). The instrument used to measure BUN and blood creatinine levels was Arkray Spotchem TM EZ 4430. Data on BUN and blood creatinine profiles of the five dogs based on time of observation were analyzed using the one way ANOVA test. The results showed that there was no significant difference in the levels of BUN and blood creatinine in dogs at various observation times (P>0.05). The average BUN and blood creatinine levels of dogs were still in the normal range. This may indicate that the administration of a single dose of Sarolaner does not affect kidney function. |
| URI: | http://repository.ipb.ac.id/handle/123456789/108266 |
| Appears in Collections: | UT - Animal Disease and Veterinary Health |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| COVER.pdf Restricted Access | Cover | 2.99 MB | Adobe PDF | View/Open |
| B04170069_Yola Salsabila Hidayah.pdf Restricted Access | Fullteks | 6 MB | Adobe PDF | View/Open |
| LAMPIRAN.pdf Restricted Access | Lampiran | 545.29 kB | Adobe PDF | View/Open |
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