Please use this identifier to cite or link to this item: http://repository.ipb.ac.id/handle/123456789/107307
Title: Profil Sebaran Panas Silinder Stainless Steel Berlapis Grafena Oksida untuk Peluang Pendeteksian Spike Glycoprotein
Authors: Sumaryada, R Tony Ibnu
Maddu, Akhiruddin
Kusuma, Ruby Teja
Issue Date: 2021
Publisher: IPB University
Abstract: Usaha awal menggunakan model termal dikembangkan untuk dapat mendeteksi keberadaan SARS-CoV-2 di lingkungan dengan memodelkan sistem yang terdiri atas ikatan antara spike glycoprotein (salah satu komponen SARSCoV-2) dan grafena oksida. Metode yang digunakan adalah metode numerik eksplisit finite difference untuk mengukur sebaran panas 1-dimensi pada sistem silinder, sebelum dan sesudah berikatan dengan spike glycoprotein. Beberapa asumsi digunakan, salah satunya spike glycoprotein disini digantikan oleh lapisan protein karena belum adanya pengukuran properti termal dari spike glycoprotein. Hasilnya adalah ditemukan perubahan distribusi temperatur sebagai manifestasi akibat digunakannya energi untuk mengikat spike glycoprotein oleh grafena oksida. Selisih energi tersebut selanjutnya dapat digunakan untuk menghitung jumlah SARS-CoV-2 yang berikatan dengan sistem silinder. Hasilnya untuk penurunan laju energi sebesar 0,011 J/s pada sistem, spike glycoprotein yang terjerap sebanyak 4,03×10^10 molekul.
Early effort using thermal model is developed to detect SARS-CoV-2 in our environment by modeling system that comprised of binding between spike glycoprotein (one of the component of SARS-CoV-2) and graphene oxide. The method used is the numeric explicit finite difference to see 1-dimensional heat profile distribution on the cylindrical system, before and after it binds with spike glycoprotein. A few assumption is made here, one of them is spike glycoprotein in here is substituted with protein layer since there are no thermal property measurement of spike glycoprotein yet. The result is that the change of temperature distribution is found as manifestation of the energy used to bind spike glycoprotein by graphene oxide. The deficit of energy is thus used to count the number of SARSCoV-2 that binds with cylindrical system. The result is for the decreasing rate of energy of the system of 0.011 J/s, there are 4.03×10^10 spike glycoprotein has been trapped.
URI: http://repository.ipb.ac.id/handle/123456789/107307
Appears in Collections:UT - Physics

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