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http://repository.ipb.ac.id/handle/123456789/102902| Title: | KOREKSI DNA SEQUENCING ERROR DENGAN METODE SPECTRAL ALIGNMENT YANG DiMODIFIKASI |
| Authors: | Almi, Gerry Indramades Kusuma, Wisnu Ananta |
| Keywords: | DNA sequencing error, spectral alignment. DNA sequence assembly, statistical approach |
| Issue Date: | 2014 |
| Publisher: | SEMIRATA 2014, |
| Abstract: | GraphbasedDNAsequenceassemblyis actuallyusedto generatecontiqsformreadsproducedby secondgenerationsequencer,However,graphbasedDNAsequenceassemblyis verysensitiveagainstsequencingerror,Theexistenceof sequencingerrorswillincreasethecomplexityof graph,Meanwhile,everyprocessof sequencingalwaysproducesequencingerrors,Thisresearchaimsto improvetheperformanceof DNA sequencing error correction base donthe spectral alignment by implementinga statistical approach. Thisapproachgeneratea spectrumof solidtupleby choosingtuplesthatbelongto thehighest75%of thetupleoccurenciesdistribution,Readscontainingsequencingerrorsarecorrectedusingtuplereferencesthatbelongto thesolidtuplespectrum,Evaluationis conductedusingVelvet.a DNA assembly software,Theresults show that ourapproach can reducethecomplexityof graphproducedby thepreviousapproach, |
| URI: | http://repository.ipb.ac.id/handle/123456789/102902 |
| ISBN: | 978-602-70491-0-9 |
| Appears in Collections: | Published By Media |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| paper_54716dea-db98-4cec-98f1-330a4934db75.pdf | 7.12 MB | Adobe PDF | View/Open |
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