Pemanfaatan rotifera jenis brachionusplicatilis sebagai biofarma untuk mengontrol hormon ghrelin yang memicu penyakit hipertensi

Abstract

It has been known that Brachionus plicatilis contain unsaturated fatty acid, so it could be used as hypocholesterolemia and hypolipidemia agents. A study about the effect Brachionus plicatilis to cholesterole and lipid blood concentration high feeding cholesterol and lipid diet white rat, has been carried out. In this observation, 15 male white rats with 150 to 200 g of weight and 8 months of age were used and divided into five groups randomly. The first group was as a normal control, the second group was given high cholesterol 1 g/day as a treatment control. For the third and the fourth groups, each of them was given with high cholesterol and lipid diet in the different quantity 1 g/day and 2 g/day. After two weeks of treatment, the blood rats was taken out from the tail and then total cholesterol and total lipid concentration were measured. The results showed that all of dosages of rotifers has lowering cholesterol and lipid effects.