Kajian Histopatologi Limpa dan Jantung Sapi yang Terinfeksi Coxiella burnetii di Rumah Potong Hewan Terpadu Kota Bogor

Abstract

Query fever is a zoonotic disease caused by Coxiella burnetii. This agent infects any kinds of animal including cattle. In many cases report, there are no clinical signs appear during the infection of C. burnetii. Then, it is also difficult to diagnose this disease. The study about infection of C. burnetii in cattle was carried out from February to October 2013 at Bogor Slaughterhouse. The aim of this study was to know the infection of C. burnetii and compare the histopathological finding of spleen and heart of infected cattle. A total of 50 samples of cattle spleen, heart, liver, kidney, and lung were collected, and processed for immunohistochemical and hematoxyllin and eosin staining. The result of immunohistochemical staining showed 5 samples were immunoreactive to polyclonal rabbit anti-Coxiella burnetii antibody FKH IPB in the spleen, liver, and kidney. The histopathological finding indicated hemosiderin pigment deposits, lymphoid follicle depletion, infiltration of lymphocyte, macrophage, neutrophil, and eosinophil cells, and oedema. No lesion appeared in heart with positive infection of C. burnetii, however myocardial degeneration, myocardial regeneration, and myocardial congestion were found in heart with negative infection of C. burnetii.