Efektivitas Pemberian Ektrak Etanol Purwoceng (Pimpinella alpina) pada Hari 1-13 Kebuntingan terhadap Keberhasilan Implantasi pada Tikus Putih (Rattus sp.)

Abstract

Purwoceng is medicinal herbs that also have ability as estrogenic compound. The study was conducted to analyse the effect of ethanol extract purwoceng on implantation site, corpus luteum number, and ratio of implantation site to corpus luteum. A total of 8 pregnant rats were used in this study. They were devided into 2 groups; control group and treated group. The pregnant rats from treated group were given ethanol extract purwoceng with dose 83,25 mg/kg body weight starting from day 1 until 13 days of pregnancy. The control group is a non treated pregnant rats. Total of implantation site, corpus luteum number, and ratio of implantation site to corpus luteum were analyzed by non-parametric methode. The result showed that ethanol extract purwoceng in treated pregnant had a higher ratio value than negative control. Total of implantation site in treated group almost equal to the total of corpus luteum. The conclusion of this study that purwoceng ethanol extract can increase the success of implantation