Gambaran Kepucatan Mukosa pada Domba saat Kondisi Anemia Buatan sebagai Padanan Anemia akibat Haemonchosis

Abstract

Haemonchosis merupakan penyakit yang disebabkan oleh cacing parasit Haemonchus contortus. Cacing ini menghisap darah pada domba sehingga menimbulkan anemia. Domba yang digunakan merupakan domba model haemonchosis untuk meneliti fenomena biologisnya. Penelitian dilakukan pada 20 ekor domba, 10 ekor domba sebagai domba kontrol dan 10 ekor domba lainnya sebagai domba perlakuan. Domba perlakuan dilakukan pengambilan darah secara berkala selama 3 hari untuk menciptakan kondisi anemia. Foto mukosa domba dan pengambilan sampel hematologi darah dilakukan pada hari pertama dan hari ketiga. Mukosa konjungtiva dan gusi domba kontrol normal konsisten sedangkan pada domba perlakuan mengalami kepucatan, Nilai red, green, blue atau (RGB) H1 dan H3 domba kontrol tidak berbeda nyata sedangkan nilai RGB domba perlakuan terdapat perbedaan nyata. Nilai saturasi oksigen domba kontrol relatif konsisten sedangkan nilai saturasi oksigen domba perlakuan mengalami penurunan. Hematologi domba mengindikasikan adanya anemia karena nilai RBC, Hb, dan PCV berada di bawah nilai normal. Pengujian independent T test pada semua variabel menyatakan bahwa perbedaan nyata (p<0,05) terjadi pada variabel saturasi oksigen, Hb, nilai Red (R) konjungtiva, dan nilai Red (R) gusi.

Haemonchosis is a disease caused by Haemonchus contortus worms. These worms suck blood from sheep and cause anemia. The haemonchosis model sheep is a sheep that can imitate a condition in an animal suffering from haemonchosis to research its biological phenomena. The study was conducted on 20 sheep. Sheep were divided into control and treatment groups. The treated sheep were subjected to periodic blood sampling for 3 days to create anemia. Photos of the sheep's gums and conjunctiva and blood collection were taken on the first and third days. The conjunctival mucosa and gums of the control sheep were consistently normal while the treated sheep encountered mucosal paleness. Red, green, blue (RGB) values of the control sheep were not significantly different, while the treated sheep's RGB values had a significant difference between H1 and H3. Oxygen saturation value of the control sheep was relatively consistent, while the oxygen saturation value of the treated sheep decreased. The sheep's hematology indicates anemia because the RBC, Hb and PCV values are below normal. Independent T test on all variables stated that significant differences (p <0,05) occurred in oxygen saturation, Hb, conjunctival Red (R), and gum Red (R).