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      • UT - School of Veterinary Medicine and Biomedical Science
      • UT - Veterinary Clinic Reproduction and Pathology
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      Efektivitas Kombinasi Dekok Daun Tanaman Keji Beling (Strobilanthes crispa (L.) Blume) dan Tanaman Kentutan (Paederia foetida) sebagai Antidiare pada Mencit

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      Date
      2023-02
      Author
      Marintan, Meilonia Az Zahra
      Sutardi, Lina Noviyanti
      Wulansari, Retno
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      Abstract
      Diare masih menjadi masalah kesehatan utama di negara berkembang. Keanekaragaman hayati yang tinggi di Indonesia, menjadi peluang penggunaan herbal sebagai salah satu solusi pengobatan diare. Herbal memiliki banyak kandungan nutrisi, mineral, dan senyawa aktif yang memiliki efek antidiare seperti tumbuhan keji beling dan kentutan. Penelitian ini bertujuan mengetahui efek dan konsentrasi terbaik antidiare dari kombinasi dekok daun keji beling dan kentutan. Kelompok perlakuan terdiri dari kelompok kontrol negatif, kelompok kontrol positif (loperamid) dan kombinasi dekok (konsentrasi 100%, 50%, 25%, dan 12,5%). Metode yang digunakan adalah proteksi dan transit intestinal pada mencit. Induksi diare menggunakan oleum ricini. Hasil penelitian menunjukkan bahwa kombinasi dekok kedua tanaman dapat menurunkan motilitas usus, mempertahankan konsistensi feses, dan memiliki nilai rasio transit intestinal yang baik. Konsentrasi 50% memiliki hasil terbaik.
       
      Diarrhea is still a major health problem in developing countries. The high biodiversity in Indonesia is an opportunity for the use of herbal plants as a solution for treating diarrhea. Herbal plants contain many nutrients, minerals, and active compounds that have anti-diarrheal effects, such as keji beling and kentutan plant. This study aims to determine the effect and the best concentration of antidiarrheals from the combination of leaf decoction of keji beling and kentutan. The group consisted of a negative control group, a positive control group (loperamide), and decoction combination (100%, 50%, 25%, and 12,5% concentrations). The method used is intestinal protection and transit in mice. Diarrhea is induced using oleum ricini. The results showed that the combination of decoction of the two plants could reduce intestinal motility, maintain stool consistency, and have a good intestinal transit ratio. The decoct concentration of 50% has the best results.
       
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      http://repository.ipb.ac.id/handle/123456789/116726
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      • UT - Veterinary Clinic Reproduction and Pathology [2187]

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      Indonesia DSpace Group 
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