Therapeutic Drugs Used Myxomatous Mitral Valve Degeneration (MMVD) in Dogs at Gasing Veterinary Hospital in Selangor,
Date
2022-07-19Author
Huey, Lynette Ong
Andriyanto
Hadi, Upik Kesumawati
Metadata
Show full item recordAbstract
Myxomatous mitral valve degeneration (MMVD) is a chronic degenerative
disease in which the cardiac valves, mainly the mitral valve, undergo leaflet
thickening or prolapse due to aging process or genetic factor. There are five stages
of MMVD in dogs, namely stage A, stage B1, stage B2, stage C, and finally stage
D. Clinical symptoms of MMVD can be seen from stage C onwards, where
congestive heart failure signs are obvious. The study aims to obtain and analyze
secondary data of the therapeutic drugs used in the treatment of MMVD at Gasing
Veterinary Hospital in the year 2021. The highest percentage of drugs used were
ACE inhibitors and positive inotropes both at 33%. Diuretics were the second most
administered drug at 26%. Other therapeutic drugs which were administered in
smaller proportions include bronchodilators at 5%, antiplatelet at 2%, and calcium
channel blocker at 1%. It was concluded that the types of drugs that were
administered in MMVD cases comprised of ACE inhibitors, positive inotropes,
diuretics, bronchodilators, antiplatelet, and calcium channel blocker. Myxomatous mitral valve degeneration (MMVD) adalah suatu penyakit
degeneratif kronik pada katup jantung yang ditandai dengan penebalan atau prolaps
katup karena proses penuaan atau faktor genetik, terutama terjadi pada katup mitral.
Terdapat lima stadium MMVD pada anjing, yaitu stadium A, stadium B1, stadium B2,
stadium C, dan terakhir stadium D. Gejala klinis MMVD dapat dilihat dari stadium C
dan seterusnya, ditandai dengan adanya gagal jantung kongestif yang terlihat jelas.
Penelitian ini bertujuan untuk mendapatkan dan menganalisis data sekunder obat
terapeutik yang digunakan dalam pengobatan MMVD di Rumah Sakit Hewan Gasing
tahun 2021. Persentase obat tertinggi yang digunakan berupa ACE inhibitor dan inotrop
positif dengan persentase keduanya sebesar 33%. Diuretik adalah obat kedua yang
paling banyak diberikan dengan persentase sebesar 26%. Obat terapeutik lain yang
diberikan dalam proporsi yang lebih kecil diantaranya bronkodilator 5%, antiplatelet
2%, dan antagonis kalsium 1%. Secara kesimpulan, jenis obat yang diberikan pada
kasus MMVD terdiri dari ACE inhibitor, inotrop positif, diuretik, bronkodilator,
antiplatelet, dan antagonis kalsium.