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      Model Matematika Ko-infeksi HIV/AIDS dan Cacar Monyet (Monkeypox)

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      Date
      2021
      Author
      Luthfiani, Dini Dessya
      Sianturi, Paian
      Kusnanto, Ali
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      Abstract
      Cacar monyet (monkeypox) adalah penyakit akibat virus yang ditularkan melalui binatang. Penularan virus cacar monyet ke manusia dari hewan seperti monyet dan hewan pengerat terjadi melalui kontak langsung atau mengonsumsi daging hewan liar yang terkontaminasi. Dalam model ini, populasi hewan dibagi menjadi tiga subpopulasi dan populasi manusia dibagi menjadi sembilan subpopulasi. Hasil analisis diperoleh titik tetap bebas penyakit dan titik tetap endemik. Hasil analisis sensitivitas menunjukkan bahwa laju penularan penyakit dan rata-rata kontak individu merupakan parameter yang paling berpengaruh dalam model. Dengan simulasi numerik, ditunjukkan juga bahwa penurunan laju penularan dan kontak individu berbanding lurus dengan penurunan bilangan reproduksi dasar sehingga berpengaruh untuk menekan peningkatan populasi individu terinfeksi. Pertumbuhan populasi individu terinfeksi juga semakin mengecil sehingga pengontrolan faktor ini akan mengakibatkan penyakit dapat dikendalikan.
       
      Monkeypox is a disease caused by a virus that is transmitted through animals. The virus transmits monkeypox to human from animals such as monkeys and rodents through direct contact or consuming contaminated wild animals meat. The animal populations consist of three subpopulations and the human populations consist of nine subpopulations. The analysis result shows that there are disease free fixed point and endemic fixed point. Sensitivity analysis suggests that the rate of transmission and individual contact are the most influential parameters in models. Numerical simulations have also shown that decrease in the rate of transmission and individual contact is proportional to the decrease of basic reproduction number, thus moderating the increase of the population of the infected individuals. The growth of infected population is also getting smaller, so that controlling these factors can control the disease.
       
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      http://repository.ipb.ac.id/handle/123456789/109819
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      Copyright © 2020 Library of IPB University
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      Indonesia DSpace Group 
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