View Item 
      •   IPB Repository
      • Dissertations and Theses
      • Undergraduate Theses
      • UT - Faculty of Mathematics and Natural Sciences
      • UT - Physics
      • View Item
      •   IPB Repository
      • Dissertations and Theses
      • Undergraduate Theses
      • UT - Faculty of Mathematics and Natural Sciences
      • UT - Physics
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      Analisis Kestabilan Protein 1GB1 Menggunakan Simulasi Dinamika Molekul

      Thumbnail
      View/Open
      full text (2.045Mb)
      Date
      2014
      Author
      Hati, Jellyta
      Sumaryada, Tony Ibnu
      Wahyudi, Setyanto Tri
      Metadata
      Show full item record
      Abstract
      A mechanism to explain the stability of the protein is still a major problem that is not fully understood. One of the problem is understanding the high thermal stability of 1GB1 protein. The thermal stability of 1GB1 protein can be analyzed using molecular dynamics simulation technique. The aim of this research is to learn molecular dynamics and thermal stability of 1GB1 protein in the range of simulation up to 100 ns. Simulation process consists of the preparation, minimization, heating, equilibration, and production run. The initial coordinate file 1GB1 can be downloaded from Protein Data Bank. The influence of thermal that given by this simulation are 450K and 475K for 100 ns, while 500K is bounded for 2 ns. For 475K simulation, the unfolding process occured at 95 ns indicated by the dissappearance of some secondary structure. For 500K simulation, the unfolding process occured at 745 ps indicated by the dissappearance of most of the secondary structure (collapsing of α-helix and β-hairpin structure).
      URI
      http://repository.ipb.ac.id/handle/123456789/69409
      Collections
      • UT - Physics [1125]

      Copyright © 2020 Library of IPB University
      All rights reserved
      Contact Us | Send Feedback
      Indonesia DSpace Group 
      IPB University Scientific Repository
      UIN Syarif Hidayatullah Institutional Repository
      Universitas Jember Digital Repository
        

       

      Browse

      All of IPB RepositoryCollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

      My Account

      Login

      Application

      google store

      Copyright © 2020 Library of IPB University
      All rights reserved
      Contact Us | Send Feedback
      Indonesia DSpace Group 
      IPB University Scientific Repository
      UIN Syarif Hidayatullah Institutional Repository
      Universitas Jember Digital Repository