| dc.contributor.author | Wresdiyati, Tutiek | |
| dc.contributor.author | Astawan, Made | |
| dc.contributor.author | Hastanti, Lusia | |
| dc.date.accessioned | 2011-03-28T03:48:58Z | |
| dc.date.available | 2011-03-28T03:48:58Z | |
| dc.date.issued | 2006 | |
| dc.identifier.issn | 0854-8587 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/43323 | |
| dc.description.abstract | This study was conducted to observe intracellular antioxidant cooper,zinc-superoxide dismutase (Cu,Zn-SOD) in liver tissue of rats under hypercholesterolemic condition by using immunohistochemical technique. A total of twenty male Wistar rats were used for this study. Those rats were divided into two groups; (i) control group and (ii) hypercholesterolemic group, which were fed died containing 1% cholesterol for eight weeks. Rat livers were taken at the end of treatment, and processed by using paraffin embedding standard method. The tissues were stained immunohistochemically to Cu,Zn-SOD. Observation of Cu,Zn-SOD content in the tissue was performed qualitatively in the cytoplasm and quantitatively in the nucleus of hepatocytes based on colour intensity of enzyme reaction product. The profile of antioxidant-Cu,Zn-SOD decreased (P < 0.05) in the hypercholesterolemic group compared to the control group. | en |
| dc.publisher | IPB (Bogor Agricultural University) | |
| dc.relation.ispartofseries | Vol 13;No 3 | |
| dc.title | The Immunohistochemical Profile of Superoxide Dismutase (SOD) in the Liver Tissue of Hypercholesterolemic Rats | en |
| dc.title.alternative | HAYATI Journal of Biosciences Vol. 13 No.3 Tahun 2006 | en |
