Isolasi Miristisin dari Minyak Pala (Myristica fragrans) dengan Metode Penyulingan Uap

Abstract

Myristicin (C11H12O3) is one of the most important constituents of the nutmeg oil. Myristicin is toxic and hallucinogenic agent in mutmeg and mace. Isolation of myristicin can be carried out by steam distillation. The objective of this research was to extract myristicin from nutmeg oil by steam distillation. Nutmeg oil was distilled at pressure 15 mmHg, 145, 150 and 155 C for concertation. The highest myristicin content in oil fraction was 70,10% with concertation 786.99 g/l obtained by distillation at 145 C. Under this operating atmospheric pressure for 2, 2,5 and 3 hours.