Osmotic Sensitivity and Cross-Resistance of Iprodione-Resistant Mutants of Cochliobolus heterostrophus

Abstract

Four resistant mutants (MIC > 1600 ìg/ml), i.e. IRE002, IRE008, IRE009 and IRE012, were isolated in a study of genetics of iprodione resistance in Cochliobolus heterostrophus after ethyl methanesulphonate mutagenesis. Osmotic sensitivity and cross-resistance of the resistant mutants were investigated. The results showed that the iprodione-resistant mutant strains were osmotically sensitive and displayed cross-resistance to some fungicides, indicating a possibility that iprodione resistance in the fungus may be controlled by pleiotropic drug resistance genes. _____________________________________________