| dc.contributor.author | Magally Romero-Tabarez | |
| dc.contributor.author | Rolf Jansen | |
| dc.contributor.author | Marita Sylla | |
| dc.contributor.author | Heinrich Lünsdorf | |
| dc.contributor.author | Susanne Häußler | |
| dc.contributor.author | Santosa, Dwi A. | |
| dc.contributor.author | Kenneth N. Timmi | |
| dc.contributor.author | Gabriella Molinari | |
| dc.date.accessioned | 2010-06-08T03:47:20Z | |
| dc.date.available | 2010-06-08T03:47:20Z | |
| dc.date.issued | 2010 | |
| dc.identifier.issn | IPB (Bogor Agricultural University) | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/27813 | |
| dc.description.abstract | We report here the discovery, isolation, and chemical and preliminary biological characterization of a new antibiotic compound, 7-O-malonyl macrolactin A (MMA), produced by a Bacillus subtilis soil isolate. MMA is a bacteriostatic antibiotic that inhibits a number of multidrug-resistant gram-positive bacterial pathogens, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and a small-colony variant of Burkholderia cepacia. MMA-treated staphylococci and enterococci were pseudomulticellular and exhibited multiple asymmetric initiation points of septum formation, indicating that MMA may inhibit a cell division function. | id |
| dc.publisher | IPB (Bogor Agricultural University) | |
| dc.title | A New Macrolactin Antibiotic From Bacillus Subtilis Active Against Methicillin-Resistant Staphylococcus Aureus, Vancomycin-Resistant Enterococci, And A Small-Colony Variant Of Burkholderia Cepacia is 7-O-Malonyl Macrolactin A. | id |
