dc.contributor.advisor | Anggraeni, Henny Endah | |
dc.contributor.author | Nisa, Tahfida Imania | |
dc.date.accessioned | 2024-07-16T08:45:42Z | |
dc.date.available | 2024-07-16T08:45:42Z | |
dc.date.issued | 2024 | |
dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/153843 | |
dc.description.abstract | Rambut merupakan salah satu aspek penting pada penampilan fisik dan kondisi kesehatan umum hewan. Mencit C57BL/6 merupakan hewan laboratorium yang melakukan barbering, perilaku ini diduga menyebabkan kerontokan rambut. Minoxidil umum digunakan untuk mengatasi kerontokan rambut, namun dapat menimbulkan efek samping seperti alergi kulit dan hipotensi. Penelitian ini bertujuan untuk mengkaji potensi ekstrak daun pandan wangi (Pandanus amaryllifolius Roxb.) sebagai alternatif untuk menumbuhkan rambut mencit C57BL/6. Penelitian ini menggunakan daun pandan wangi yang dikeringkan pada suhu 40°C-50°C, dihaluskan, dan dimaserasi dalam etanol 70%. Ekstrak daun pandan diformulasikan dalam bentuk gel dengan konsentrasi 5%, 10%, dan 15%. Mencit jantan galur C57BL/6 dicukur dan diberi perlakuan setiap hari selama 21 hari. Pengamatan panjang rambut dilakukan setiap minggu, dan data yang diperoleh dianalisis menggunakan SPSS 26. Hasil penelitian menunjukkan bahwa gel ekstrak daun pandan wangi dengan konsentrasi 15% paling efektif menumbuhkan rambut mencit, dengan rata-rata panjang rambut 7,958 mm dibandingkan dengan gel minoxidil (5,711 mm) pada hari ke-21. Simpulan dari penelitian ini, sediaan gel ekstrak daun pandan wangi konsentrasi 15%, lebih efektif dalam menumbuhkan rambut mencit C57BL/6 dibandingkan dengan minoxidil. | |
dc.description.abstract | Hair is an essential aspect of physical appearance and overall health in animals. C57BL/6 mice are laboratory animals that exhibit barbering behavior, which is suspected to cause hair loss. Minoxidil is commonly used to treat hair loss, but it can causes side effects such as skin allergies and hypotension. This study aims to investigate the potential of Pandanus amaryllifolius Roxb. (pandan wangi) leaf extract as an alternative for promoting hair growth in C57BL/6 mice. This study used pandan wangi leaves were dried at temperatures of 40°C–50°C, ground, and macerated in 70% ethanol. The leaf extract was formulated into a gel with concentrations of 5%, 10%, and 15%. Male C57BL/6 mice were shaved and treated daily for 21 days. Hair length observations were conducted weekly, and the data were analyzed using SPSS 26. The research so that the 15% concentration of pandan wangi leaf extract is the most effective in promoting hair growth in C57BL/6 mice, with an average hair length of 7,958 mm compared to minoxidil gel (5,711 mm) on day 21. The conclusion of this study is that the 15% pandan wangi leaf extract gel formulation is the more effective in promoting hair growth in C57BL/6 mice compared to minoxidil. | |
dc.description.sponsorship | | |
dc.language.iso | id | |
dc.publisher | IPB University | id |
dc.title | Efektivitas Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) terhadap Pertumbuhan Rambut Mencit C57BL/6.  | id |
dc.title.alternative | Effectiveness of Pandan Wangi Leaf Extract (Pandanus amaryllifolius Roxb.) on Hair Growth of C57BL/6 Mice. | |
dc.type | Tugas Akhir | |
dc.subject.keyword | alopecia | id |
dc.subject.keyword | mencit C57BL/6 | id |
dc.subject.keyword | pandan wangi | id |
dc.subject.keyword | pertumbuhan rambut | id |
dc.subject.keyword | sediaan gel | id |