Development of Hepatocytes Primary Cultures from Tupaia javanica for Hepatitis B Virus Isolation and Detection.

Pengembangan Kultur Primer Hepatosit Tupaia javanica Sebagai Media Isolasi dan Deteksi Virus Hepatitis B

dc.contributor.advisor	Soejoedono, Retno D.
dc.contributor.advisor	Pamungkas, Joko
dc.contributor.author	Ricky
dc.date.accessioned	2013-08-20T07:35:36Z
dc.date.available	2013-08-20T07:35:36Z
dc.date.issued	2013
dc.identifier.uri	http://repository.ipb.ac.id/handle/123456789/64971
dc.description.abstract	Human hepatitis B virus is a major health problem worldwide which have a very narrow host range. The susceptibility of Tupaia belangeri hepatocytes primary culture has been used as an alternative in vitro model for studying hepatitis B virus infection. In this research, we proposed the usage of T. javanica hepatocytes primary culture as an in vitro model to isolate and detect hepatitis B virus from human and Hylobates moloch. Both in vitro infection of the hepatitis B virus in T. javanica hepatocytes primary culture show viral DNA replication in Real Time PCR. The result suggest that T. javanica may become a useful model for studying hepatitis B virus infecton	en
dc.subject	Hepatitis B virus	en
dc.subject	Tupaia javanica	en
dc.subject	primary hepatocytes	en
dc.subject	Hylobates moloch	en
dc.subject	real time PCR	en
dc.title	Development of Hepatocytes Primary Cultures from Tupaia javanica for Hepatitis B Virus Isolation and Detection.	en
dc.title	Pengembangan Kultur Primer Hepatosit Tupaia javanica Sebagai Media Isolasi dan Deteksi Virus Hepatitis B