| dc.description.abstract | Klebsiella pneumoniae belongs to the family Enterobacteriaceae and is found
in mouth and intestine. Klebsiella pneumoniae has been reported in various
nonhuman primate species with the cases of pneumonia, septicemia, and enteritis.
This secondary study purposed to obtain information of clinical pathology profile
related to Klebsiella infection in cynomolgus monkeys (Macaca fascicularis). This
secondary study was conducted on three long-tailed monkeys which showed
positive results in the bacterial culture test. The secondary study was based on blood
analysis to evaluate hematology and blood chemistry. The results demonstrate that
monkeys with Klebsiella pneumoniae exhibited marked changes in erythrocytes,
hemoglobin, hematocrit and mean corpuscular hemoglobin concentration values in
hematology as well as creatinine, total protein, and albumin levels and
albumin/globulin ratio in blood chemistry profile. The changes may indicate the
incidence of anemia, liver disease, thrombocytopenia, dehydration, inflammatory
response and kidney disease, which may be associated with Klebsiella pneumoniae
infection. | id |
